Evaluation of Chagas' disease transmission through breast-feeding

One hundred milk or colostrum samples from 78 mothers with chronic Chagas' disease were parasitologically studied for Trypanosoma cruzi infection by means of direct examination and inoculation of mice. The mice were submitted to direct blood examination three times a week. At the end of 45 days...

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Bibliographic Details
Published in:Memórias do Instituto Oswaldo Cruz 1988, Vol.83 (1), p.37-39
Main Authors: BITTENCOURT, A. L, SADIGURSKY, M, DA SILVA, A. A, MENEZES, C. A. S, MARIANETTI, M. M. M, GUERRA, S. C, SHERLOCK, I
Format: Article
Language:English
Subjects:
Animals
Antibodies, Protozoan - analysis
Biological and medical sciences
Breast Feeding
Chagas Disease - diagnosis
Chagas Disease - transmission
Colostrum - analysis
Colostrum - parasitology
Female
Human protozoal diseases
Humans
Immunoglobulin G - analysis
Infant
Infectious diseases
Medical sciences
Mice
Milk, Human - analysis
Milk, Human - parasitology
Parasitic diseases
PARASITOLOGY
Protozoal diseases
Serologic Tests
TROPICAL MEDICINE
Trypanosoma cruzi - immunology
Trypanosomiasis
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Summary:One hundred milk or colostrum samples from 78 mothers with chronic Chagas' disease were parasitologically studied for Trypanosoma cruzi infection by means of direct examination and inoculation of mice. The mice were submitted to direct blood examination three times a week. At the end of 45 days, xenodiagnosis and indirect immunofluorescent test (IFAT) for T. cruzi antibodies were carried out in the animals. No parasitized sample was observed even though five mothers had parasitemia at milk collection. In addition, 97 breast-fed children of chronic chagasic mothers, born free of infection, were tested for IgG antibodies to T. cruzi using IFAT. No case of T. cruzi infection was detected. The authors conclude that breast-feeding should not be avoided for children of chronic chagasic women. However, as these mothers had intermittent parasitemia, they should avoid nursing when there is nipple bleeding.
ISSN:0074-0276
1678-8060
1678-8060
0074-0276
DOI:10.1590/s0074-02761988000100005