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Assessment of Preoperative Endometrial Histopathological Sampling as a Predictor of Final Surgical Pathology in Endometrial Cancer

To evaluate the agreement between the histopathological diagnoses of preoperative endometrial samples and surgical specimens and correlate the agreement between the diagnoses with the impact on surgical management and the survival of patients with endometrial adenocarcinomas.  Sixty-two patients tre...

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Bibliographic Details
Published in:Revista Brasileira de ginecologia e obstetrícia 2020-10, Vol.42 (10), p.642-648
Main Authors: Piotto, Mario Augusto Silveira Bueno, Focchi, Gustavo Rubino de Azevedo, Marques, Renato Moretti, Teixeira, Andressa Melina Severino, Gonçalves, Wagner José, Nicolau, Sergio Mancini
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Language:English
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Summary:To evaluate the agreement between the histopathological diagnoses of preoperative endometrial samples and surgical specimens and correlate the agreement between the diagnoses with the impact on surgical management and the survival of patients with endometrial adenocarcinomas.  Sixty-two patients treated for endometrial cancer at a university hospital from 2002 to 2011 were retrospectively evaluated. The histopathological findings of preoperative endometrial samples and of surgical specimens were analyzed. The patients were subjected to hysterectomy as well as adjuvant treatment, if necessary, and clinical follow-up, according to the institutional protocol. Lesions were classified as endometrioid tumor (type 1) grades 1, 2, or 3 or non-endometrioid carcinoma (type 2).  The agreement between the histopathological diagnoses based on preoperative endometrial samples and surgical specimens was fair (Kappa: 0.40;  
ISSN:0100-7203
1806-9339
1806-9339
DOI:10.1055/s-0040-1713802