Nipple-sparing Mastectomy with Immediate Implant-based Reconstruction for Patients with Pure Ductal Carcinoma in Situ

The presence of an extensive intraductal component is associated to an increasing risk of relapse in the nipple-areola complex. The aim of the present study was to evaluate the outcomes of patients diagnosed with ductal carcinoma in situ (DCIS) who underwent nipple-sparing mastectomy (NSM) with imme...

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Published in:Revista Brasileira de ginecologia e obstetrícia 2022-04, Vol.44 (4), p.376-384
Main Authors: Frasson, Antônio Luiz, Falcone, Ana Beatriz, Miranda, Isabela, Souza, Alessandra Borba Anton de, Vollbrecht, Betina, Barbosa, Fernanda, Frasson, Mônica Adriana Rodriguez Martinez, Lichtenfels, Martina
Format: Article
Language:English
Subjects:
Breast Implantation
Breast Neoplasms - surgery
Carcinoma, Intraductal, Noninfiltrating
Female
Humans
Mastectomy
Nipples - surgery
OBSTETRICS & GYNECOLOGY
Original
Retrospective Studies
Silicones
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Summary:The presence of an extensive intraductal component is associated to an increasing risk of relapse in the nipple-areola complex. The aim of the present study was to evaluate the outcomes of patients diagnosed with ductal carcinoma in situ (DCIS) who underwent nipple-sparing mastectomy (NSM) with immediate breast reconstruction using silicone implants.  We retrospectively analyzed the postoperative complications and oncological safety of 67 breast cancer patients diagnosed with pure DCIS who underwent NSM with immediate breast reconstruction using silicone implants between 2004 and 2018.  Among the 127 NSM procedures performed, 2 hematomas (1.5%) and 1 partial nipple necrosis (0.7%) were observed. After a mean follow-up of 60 months, the local recurrence rate was of 8.9%, the disease-free survival rate was of 90%, and 1 of the patients died.  Despite the local recurrence rate, we showed that NSM with immediate breast reconstruction using silicone implants is a feasible surgical approach, with a low rate of complications and high survival rates for patients with a diagnosis of pure DCIS when breast-conserving surgery is not an option.
ISSN:0100-7203
1806-9339
1806-9339
DOI:10.1055/s-0042-1742315