Sesquiterpenoids of Senecio bonariensis Hook. & Arn., Asteraceae

From the leaves of Senecio bonariensis Hook. & Arn. three sesquiterpenoids were isolated. β-caryophyllene (1), β-caryophyllene oxide (2) and germacrene D (3) were characterized by GC-EI-MS, IR, ¹H and 13C-NMR data. Their ecological and chemotaxonomical significance for the genus Senecio are disc...

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Bibliographic Details
Published in:Revista brasileira de farmacognosia 2010-03, Vol.20 (1), p.87-92
Main Authors: Silva, Chana de Medeiros da, Bolzan, Aline Abati, Mallmann, Carlos Augusto, Pozzatti, Patrícia, Alves, Sydney Hartz, Heinzmann, Berta Maria
Format: Article
Language:English
Subjects:
PHARMACOLOGY & PHARMACY
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Summary:From the leaves of Senecio bonariensis Hook. & Arn. three sesquiterpenoids were isolated. β-caryophyllene (1), β-caryophyllene oxide (2) and germacrene D (3) were characterized by GC-EI-MS, IR, ¹H and 13C-NMR data. Their ecological and chemotaxonomical significance for the genus Senecio are discussed, as well as the biosynthetic correlation between the isolated substances. The antimicrobial activity of substances 1 and 2 were evaluated by the microdilution method against bacterial and fungal strains. Both compounds did not inhibit the microorganism growth at the tested concentrations.
ISSN:0102-695X
1981-528X
DOI:10.1590/S0102-695X2010000100018