Aspergillus niger: A Hundred Years of Contribution to the Natural Products Chemistry

Aspergillus niger is a phytopathogenic fungus responsible for the plant disease called “black mold”, and it is considered the most versatile microorganism for producing acids, proteins, and enzymes of industrial value, besides a variety of compounds of pharmacological interest. This review presents...

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Bibliographic Details
Published in:Journal of the Brazilian Chemical Society 2019-10, Vol.30 (10), p.2029-2059
Main Authors: Lima, Mary Anne, de Oliveira, Maria da Conceição, Pimenta, Antônia, Uchôa, Paula
Format: Article
Language:English
Subjects:
CHEMISTRY, MULTIDISCIPLINARY
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Summary:Aspergillus niger is a phytopathogenic fungus responsible for the plant disease called “black mold”, and it is considered the most versatile microorganism for producing acids, proteins, and enzymes of industrial value, besides a variety of compounds of pharmacological interest. This review presents a century of contribution of A. niger in the natural products chemistry under two different perspectives: (i) an overview of the structural diversity of secondary metabolites produced by A. niger from different habitats and their biological activities; (ii) a general discussion of the enzymatic potential of A. niger on the selective biotransformation of terpenes, highlighting the most uncommon microbial transformations.
ISSN:0103-5053
1678-4790
DOI:10.21577/0103-5053.20190080