Clinical and epidemiological profile of patients in the chronic phase of Chagas disease treated at a reference center in Southeastern Brazil

• Published in: Revista de la Facultad de Medicina, Universidad Nacional de Colombia Universidad Nacional de Colombia, 2020-09, Vol.68 (3), p.391-398
• Main Authors: Zanella, Luiz Gonzaga Francisco de Assis Barros D'Elia, Galiano, Isabela Walder, Martins, Cintia Perinetti Alves, Tokumo, Maurício Ossamu, Suzuki, Rodrigo Buzinara, Chagas, Eduardo Federighi Baisi, Martins, Luciamáre Perinetti Alves
• Format: Article
• Language: eng ; por
• Subjects: MEDICINE, GENERAL & INTERNAL
• ISSN: 0120-0011
• DOI: 10.15446/revfacmed.v68n3.76191

Abstract Introduction: After implementing measures to control vector transmission by Triatoma infestans in Brazil, the number of new cases of Chagas disease (CD) decreased. Currently, the American continent has an annual incidence of 28 000 cases, but a large number of older adults are still affected by the chronic phase of this disease. Objective: To characterize the clinical and epidemiological profile of patients in the chronic phase of CD treated at a reference center located in the state of São Paulo, Brazil. Materials and methods: A cross-sectional, descriptive study was conducted based on the analysis of the medical records of 62 patients in the chronic phase of CD and treated at the Hospital das Clínicas de Marília. Results: No significant differences were found regarding sex, age and time of diagnosis. Cardiac problems were the most reported clinical sign. A significant difference was observed in the case of the indeterminate form of the disease, which was more predominant in males. In addition, functional classification B1 of CD was more common in women, while B2 predominated in men. Conclusion: A late diagnosis of CD may increase the chances of presenting digestive complications. However, the classic manifestations of the disease and its comorbidities can be successfully managed as long as comprehensive (multidisciplinary) medical care is provided, since this would help delay the course of the disease and, consequently, improve the patients' quality of life.