Prevalence of autoantibodies in a group of hereditary angioedema patients

Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AA...

Full description

Saved in:
Bibliographic Details
Published in:Anais brasileiros de dermatología 2012-03, Vol.87 (2), p.332-334
Main Authors: Dortas Junior, Sergio Duarte, Valle, Solange Oliveira Rodrigues, Levy, Soloni Afra Pires, Tortora, Rosangela P, Abe, Augusto Tiaqui, Pires, Gisele Viana, Papi, José Angelo de Souza, França, Alfeu Tavares
Format: Article
Language:English
Subjects:
Adult
Angioedemas, Hereditary - immunology
Autoantibodies - blood
DERMATOLOGY
Female
Humans
Male
Prevalence
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AAB so that individuals at risk of developing autoimmune diseases can be identified. Fifteen patients with Hereditary Angioedema attended at Clementino Fraga Filho University Hospital accepted to participate in this study. Prevalence of AAB was 40%. Our data indicate high prevalence of AAB in patients with Hereditary Angioedema. Large-scale studies should be considered to determine the significance of these AAB in the follow-up care of patients with Hereditary Angioedema.
ISSN:0365-0596
1806-4841
1806-4841
0365-0596
DOI:10.1590/S0365-05962012000200030