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Prevalence of autoantibodies in a group of hereditary angioedema patients

Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AA...

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Published in:	Anais brasileiros de dermatología 2012-03, Vol.87 (2), p.332-334
Main Authors:	Dortas Junior, Sergio Duarte, Valle, Solange Oliveira Rodrigues, Levy, Soloni Afra Pires, Tortora, Rosangela P, Abe, Augusto Tiaqui, Pires, Gisele Viana, Papi, José Angelo de Souza, França, Alfeu Tavares
Format:	Article
Language:	English
Subjects:	Adult Angioedemas, Hereditary - immunology Autoantibodies - blood DERMATOLOGY Female Humans Male Prevalence
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container_title	Anais brasileiros de dermatología
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creator	Dortas Junior, Sergio Duarte Valle, Solange Oliveira Rodrigues Levy, Soloni Afra Pires Tortora, Rosangela P Abe, Augusto Tiaqui Pires, Gisele Viana Papi, José Angelo de Souza França, Alfeu Tavares
description	Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AAB so that individuals at risk of developing autoimmune diseases can be identified. Fifteen patients with Hereditary Angioedema attended at Clementino Fraga Filho University Hospital accepted to participate in this study. Prevalence of AAB was 40%. Our data indicate high prevalence of AAB in patients with Hereditary Angioedema. Large-scale studies should be considered to determine the significance of these AAB in the follow-up care of patients with Hereditary Angioedema.
doi_str_mv	10.1590/S0365-05962012000200030
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subjects	Adult Angioedemas, Hereditary - immunology Autoantibodies - blood DERMATOLOGY Female Humans Male Prevalence
title	Prevalence of autoantibodies in a group of hereditary angioedema patients
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