Congenital and neonatal lupus erythematosus: two case reports

Neonatal lupus erythematosus is an autoimmune disease produced by the passage of maternal antinuclear antibodies and extractable nuclear antigen antibodies through the placenta. At the moment of the diagnosis, the mothers are asymptomatic in 40 to 60% of cases. The most common manifestations are cut...

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Bibliographic Details
Published in:Anais brasileiros de dermatología 2012-07, Vol.87 (4), p.625-628
Main Authors: Frey, Marcos Noronha, Ioppi, Ana Elisa Empinotti, Garbin, Gabriela Czarnobay, Furian, Roque Domingos, Bau, Ana Elisa Kiszewski
Format: Article
Language:English
Subjects:
Antibodies, Antinuclear - blood
DERMATOLOGY
Female
Humans
Infant
Infant, Newborn
Infant, Newborn, Diseases - diagnosis
Lupus Erythematosus, Cutaneous - congenital
Lupus Erythematosus, Cutaneous - diagnosis
Remission, Spontaneous
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Summary:Neonatal lupus erythematosus is an autoimmune disease produced by the passage of maternal antinuclear antibodies and extractable nuclear antigen antibodies through the placenta. At the moment of the diagnosis, the mothers are asymptomatic in 40 to 60% of cases. The most common manifestations are cutaneous lesions and congenital heart block. The cutaneous findings are variable and usually begin within the first weeks or months of life. Congenital lupus erythematosus is a congenital variant of neonatal lupus erythematosus. We present one case of congenital lupus erythematosus and one case of neonatal lupus erythematous, showing the variability of this disease.
ISSN:0365-0596
1806-4841
1806-4841
0365-0596
DOI:10.1590/S0365-05962012000400019