Low level laser therapy (AlGaInP) applied at 5J/cm2 reduces the proliferation of Staphylococcus aureus MRSA in infected wounds and intact skin of rats

• Published in: Anais brasileiros de dermatología 2013-01, Vol.88 (1), p.50-55
• Main Authors: Silva, Daniela Conceição Gomes Gonçalves e, Plapler, Helio, Costa, Mateus Matiuzzi da, Silva, Silvio Romero Gonçalves e, Sá, Maria da Conceição Aquino de, Silva, Benedito Sávio Lima e
• Format: Article
• Language: English
• Subjects: Analysis of Variance; Animals; Colony Count, Microbial; DERMATOLOGY; Disease Models, Animal; Investigation; Low-Level Light Therapy - methods; Male; Methicillin-Resistant Staphylococcus aureus - growth & development; Methicillin-Resistant Staphylococcus aureus - radiation effects; Radiation Dosage; Random Allocation; Rats; Rats, Wistar; Staphylococcal Infections - radiotherapy; Statistics, Nonparametric; Wound Healing - radiation effects; Wound Infection - microbiology; Wound Infection - radiotherapy
• ISSN: 0365-0596; 1806-4841; 1806-4841; 0365-0596
• DOI: 10.1590/S0365-05962013000100005

Laser therapy is a low cost, non-invasive procedure with good healing results. Doubts exist as to whether laser therapy action on microorganisms can justify research aimed at investigating its possible effects on bacteria-infected wounds. To assess the effect of low intensity laser on the rate of bacterial contamination in infected wounds in the skin of rats. An experimental study using 56 male Wistar rats. The animals were randomly divided into eight groups of seven each. Those in the "infected" groups were infected by Staphylococcus aureus MRSA in the dorsal region. Red laser diode (AlGaInP) 658nm, 5J/cm2 was used to treat the animals in the "treated" groups in scan for 3 consecutive days. Samples were drawn before inoculating bacteria and following laser treatment. For statistical analysis we used the nonparametric Wilcoxon (paired data) method with a significance level of p