The desmoplastic limph node reaction as a prognostic factor of cancer of the tongue and floor of the mouth

• Published in: São Paulo medical journal 1994-09, Vol.112 (3), p.591-596
• Main Authors: Lehn, Carlos Neutzling, Rapoport, Abrão
• Format: Article
• Language: English
• Subjects: Desmoplasia; Extracapsular spread; Lymph node; MEDICINE, GENERAL & INTERNAL
• ISSN: 1516-3180; 1806-9460; 1516-3180
• DOI: 10.1590/S1516-31801994000300004

To determine the prognostic significance of desmoplasia in metastatic lymph nodes of squamous cell carcinoma of the oral tongue and floor of mouth, 37 cases of this disease were studied. Desmoplasia was present in 59,4% of the cases and associated extracapsular spread in 40,5%. The association of desmoplasia with large lymph node involvement occurred in 59,4%. These relationships were statistically significant (p= 0,002 and 0,0069). The results obtained suggest that desmoplasia is a bad prognosis associated factor. Para determinar o significado do prognóstico da desmoplasia nos linfonodos metastáticos de carcinoma epidermóide da língua oral e do soalho da boca, 37 casos desta doença foram estudados. Desmoplasia estava presente em 59,4% dos casos e associada com rotura capsular em 40,5%. A associação de desmoplasia com envolvimento linfonodal extenso ocorreu em 59,4%. Estas relações foram estatisticamente significantes (p= 0,002 e 0,0069). Os resultados obtidos sugerem que a desmoplasia é um fator associado com mau prognóstico.