Low frequency of bipolar disorder, dopamine dysregulation syndrome, and punding in Brazilian patients with Parkinson's disease

To investigate the frequency of bipolar disorder, dopamine dysregulation syndrome and punding in Parkinson's disease patients from a Brazilian movement disorders clinic. One hundred patients underwent a comprehensive psychiatric examination composed of MINI-plus and specific questionnaires to i...

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Bibliographic Details
Published in:Revista brasileira de psiquiatria 2010-03, Vol.32 (1), p.62-65
Main Authors: Kummer, Arthur, Dias, Fernando M V, Cardoso, Francisco, Teixeira, Antonio L
Format: Article
Language:English
Subjects:
Adult
Age of Onset
Aged
Antiparkinson Agents - adverse effects
Bipolar Disorder - diagnosis
Brazil - epidemiology
Confidence Intervals
Dopamine - physiology
Dopamine Agents - adverse effects
Female
Humans
Levodopa - therapeutic use
Male
Middle Aged
Parkinson Disease - drug therapy
Parkinson Disease - epidemiology
Parkinson Disease - psychology
PSYCHIATRY
Stereotyped Behavior
Syndrome
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Summary:To investigate the frequency of bipolar disorder, dopamine dysregulation syndrome and punding in Parkinson's disease patients from a Brazilian movement disorders clinic. One hundred patients underwent a comprehensive psychiatric examination composed of MINI-plus and specific questionnaires to investigate dopamine dysregulation syndrome and punding. We identified, respectively, one and five Parkinson's disease patients with bipolar disorder type I and type II. All manic/hypomanic episodes occurred before Parkinson's disease onset. No patient was identified with dopamine dysregulation syndrome or punding. The frequency of manic/hypomanic episodes seems to decrease with Parkinson's disease onset, and local environmental factors (e.g. drug availability) may be responsible for the low frequency of dopamine dysregulation syndrome and punding in Brazilian Parkinson's disease patients.
ISSN:1516-4446
1809-452X
1516-4446
DOI:10.1590/S1516-44462010000100012