Serum total IgE levels and total eosinophil counts: relationship with treatment response in patients with acute asthma

To determine whether serum total IgE levels and total eosinophil counts have any relationship with the response to routine pharmacological treatment in patients with acute asthma. A cross-sectional study involving 162 patients with acute asthma. Serum total IgE levels, peripheral blood cell counts a...

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Bibliographic Details
Published in:Jornal brasileiro de pneumologia 2010-01, Vol.36 (1), p.23-28
Main Authors: Razi, Ebrahim, Moosavi, Gholam Abbass
Format: Article
Language:eng ; por
Subjects:
Acute Disease
Adult
Asthma - drug therapy
Asthma - immunology
Biomarkers - blood
Cross-Sectional Studies
Eosinophils - cytology
Female
Humans
Immunoglobulin E - blood
Leukocyte Count
Male
Predictive Value of Tests
RESPIRATORY SYSTEM
Statistics, Nonparametric
Treatment Outcome
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Summary:To determine whether serum total IgE levels and total eosinophil counts have any relationship with the response to routine pharmacological treatment in patients with acute asthma. A cross-sectional study involving 162 patients with acute asthma. Serum total IgE levels, peripheral blood cell counts and eosinophil counts were determined. The treatment was adjusted for each patient according to the severity of asthma. Spirometry was performed at baseline and two weeks after the treatment. The patients were divided into two groups: high IgE (>100 IU/mL) and low IgE (
ISSN:1806-3713
1806-3756
1806-3756
1806-3713
DOI:10.1590/S1806-37132010000100006