Microtomographic and histological evaluation of two bioceramics as pulp capping agents in vivo

• Published in: Acta odontológica latinoamericana 2024-09, Vol.37 (2), p.179-187
• Main Authors: Torres-Flamenco, Diana, Jiménez-Castellanos, Reneé, Pérez-Sánchez, Lucía, Llaguno-Munive, Monserrat, González-Alva, Patricia, Vázquez-Vázquez, Febe Carolina, Ortiz-Magdaleno, Marine, Serrano-Bello, Janeth
• Format: Article
• Language: English
• Subjects: Aluminum Compounds - pharmacology; Animals; Calcium Compounds - pharmacology; Calcium Compounds - therapeutic use; Ceramics - pharmacology; Dental Pulp - drug effects; Dental Pulp - pathology; Dental Pulp Capping - methods; DENTISTRY, ORAL SURGERY & MEDICINE; Drug Combinations; Male; Original; Oxides - pharmacology; Oxides - therapeutic use; Pulp Capping and Pulpectomy Agents - pharmacology; Pulp Capping and Pulpectomy Agents - therapeutic use; Rats; Rats, Wistar; Silicates - pharmacology; Silicates - therapeutic use; X-Ray Microtomography
• ISSN: 1852-4834; 0326-4815; 1852-4834
• DOI: 10.54589/aol.37/2/179

Maintaining pulp vitality and function is a priority of the medicaments employed in pulp therapy to preserve tooth integrity. Aim: This study evaluated inflammatory response and reparative dentin bridge formation after direct pulp capping with two different bioceramics. Materials and Method: This was an in vivo controlled experimental study on 12 male Wistar rats. Pulpotomies were performed and the exposed pulps were capped with Biodentine or Neo MTA. After 15, 45 and 90 days, maxillary segments were obtained and prepared for histologic analysis and Micro-CT. Hounsfield Units (HU) were quantified. Results: Micro-CT analysis showed greater mineralization at 90 days with Neo MTA than with Biodentine. HU did not differ significantly (p >0.05) between molars treated with Biodentine and Neo MTA at 15 and 45 days, but at 90 days, there was statistically significant difference (p