Oral vaccination with inhibin DNA vaccine for promoting spermatogenesis in rats

The objective of the present study was to evaluate the effects of a novel Inhibin (INH) DNA vaccine (C500/pVAX-asd-IS) on the immune response, reproductive hormone levels, and spermatogenesis of rats. Forty healthy male rats were divided into four groups, and respectively immunized (thrice, 14 d apa...

Full description

Saved in:
Bibliographic Details
Published in:Animal reproduction 2024-01, Vol.21 (4), p.e20230079
Main Authors: Meng, Jinzhu, Feng, Jianhao, Xiao, Lilin, Hu, Nan, Lan, Xianyong, Wang, Shuilian
Format: Article
Language:English
Subjects:
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Original
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective of the present study was to evaluate the effects of a novel Inhibin (INH) DNA vaccine (C500/pVAX-asd-IS) on the immune response, reproductive hormone levels, and spermatogenesis of rats. Forty healthy male rats were divided into four groups, and respectively immunized (thrice, 14 d apart) with 1×10 , 1×10 , and 1×10 CFU of the recombinant inhibin vaccine (group C500/pVAX-asd-IS-L, C500/pVAX-asd-IS-M, and C500/pVAX-asd-IS-H) or 1×10 CFU C500. P/N values increased after vaccination and differed (
ISSN:1806-9614
1984-3143
1984-3143
DOI:10.1590/1984-3143-AR2023-0079