Analysis of Diastolic Left Ventricular Function in Adolescents with Juvenile Systemic Lupus Erythematosus

Abstract Background Juvenile systemic lupus erythematosus (JSLE) is a chronic inflammatory disease that affects the heart in 50% of cases. The behavior of diastolic function in adolescents and the predictors of its occurrence by conventional echocardiography are poorly established. Objectives This s...

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Bibliographic Details
Published in:International journal of cardiovascular sciences 2021-12, Vol.34 (6), p.675-684
Main Authors: Loureiro, Talita Nolasco, Valete, Cristina Ortiz Sobrinho, Castier, Marcia Bueno, Leite, Maria de Fatima Monteiro, Sztajnbok, Flavio Roberto
Format: Article
Language:English
Subjects:
CARDIAC & CARDIOVASCULAR SYSTEMS
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Summary:Abstract Background Juvenile systemic lupus erythematosus (JSLE) is a chronic inflammatory disease that affects the heart in 50% of cases. The behavior of diastolic function in adolescents and the predictors of its occurrence by conventional echocardiography are poorly established. Objectives This study aimed to evaluate diastolic function in adolescents with JSLE and to identify possible predictors of its occurrence by conventional echocardiography. Methods Cross-sectional, observational, control group study in a tertiary hospital of 49 adolescents with JSLE and 49 controls, using the EACVI 2016 guideline classification. Statistical methods used were Fisher and Mann-Whitney tests. Multivariate logistic regression models were constructed. A significance level of 5% was adopted. Results Among 98 patients, the JSLE group had higher indexed left atrial volume (p
ISSN:2359-4802
2359-5647
2359-5647
DOI:10.36660/ijcs.20200210