Three-dimensional imaging of absolute blood flow velocity and blood vessel position under low blood flow velocity based on Doppler signal information included in scattered light from red blood cells

The development of a system for in vivo visualization of occluded distal blood vessels for diabetic patients is the main target of our research. We herein describe two-beam multipoint laser Doppler velocimetry (MLDV), which measures the instantaneous multipoint flow velocity and can be used to obser...

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Bibliographic Details
Published in:Journal of applied physics 2017-11, Vol.122 (19)
Main Authors: Kyoden, Tomoaki, Akiguchi, Shunsuke, Tajiri, Tomoki, Andoh, Tsugunobu, Hachiga, Tadashi
Format: Article
Language:English
Subjects:
Applied physics
Blood flow
Blood vessels
Erythrocytes
Flow velocity
Laser beams
Laser doppler velocimeters
Medical imaging
Skin
Three dimensional flow
Velocimetry
Velocity distribution
Velocity measurement
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Summary:The development of a system for in vivo visualization of occluded distal blood vessels for diabetic patients is the main target of our research. We herein describe two-beam multipoint laser Doppler velocimetry (MLDV), which measures the instantaneous multipoint flow velocity and can be used to observe the blood flow velocity in peripheral blood vessels. By including a motorized stage to shift the measurement points horizontally and in the depth direction while measuring the velocity, the path of the blood vessel in the skin could be observed using blood flow velocity in three-dimensional space. The relationship of the signal power density between the blood vessel and the surrounding tissues was shown and helped us identify the position of the blood vessel. Two-beam MLDV can be used to simultaneously determine the absolute blood flow velocity distribution and identify the blood vessel position in skin.
ISSN:0021-8979
1089-7550
DOI:10.1063/1.4994080