Effects of pH changes in water-based solvents to isolate antibacterial activated extracts of natural products

Effects of pH changes in solvents on isolation of antibacterial activities of natural product extracts were conducted in the present study. Sarang semut (M. pendens) tubers as the model material for the study was considered to be the strategic resource of natural products based on its biochemical an...

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Bibliographic Details
Main Authors: Buang, Yohanes, Suwari, Ola, Antonius R. B.
Format: Conference Proceeding
Language:English
Subjects:
Maceration
Natural products
Solvents
Online Access:Get full text
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Summary:Effects of pH changes in solvents on isolation of antibacterial activities of natural product extracts were conducted in the present study. Sarang semut (M. pendens) tubers as the model material for the study was considered to be the strategic resource of natural products based on its biochemical and therapeutical effects. The water with pH 5, 7, 9, and 13 was used as the solvents. The antibacterial activities of the resulted extracts indicated that higher the working pH, higher activities of the resulted extracts. The extent activities of the resulted extracts followed the increasing pH of the maceration system. The study also found that higher pH of the working solvent, higher the amounts of the antibacterial extracts isolated from the sample matrix of the natural product. The higher pH of the water solvents plays essential roles to promote the antibacterial activities of the natural product extracts from M. pendens tubers.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.5015997