Preparation and properties of biocompatible PCL-PEG-PCL(PCEC)

In this work, the ring-opening polymerization of ε-caprolactone was performed, and the structure and properties of the copolymer were characterized. Copolymerization of PEG into PCL is expected to improve the hydrophilicity and degradation properties of PCL. In our study. We have studied the effect...

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Main Authors: Zhu, Yazhi, Zhong, Mingqiang, Chen, Feng
Format: Conference Proceeding
Language:English
Subjects:
Biocompatibility
Copolymerization
Molecular weight
Properties (attributes)
Reaction time
Ring opening polymerization
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Zhong, Mingqiang
Chen, Feng
description In this work, the ring-opening polymerization of ε-caprolactone was performed, and the structure and properties of the copolymer were characterized. Copolymerization of PEG into PCL is expected to improve the hydrophilicity and degradation properties of PCL. In our study. We have studied the effect of various factors on the block polymer of PCL-PEG-PCL by changing the reaction time, reaction concentration and the ratio of CL/PEG, then provided a basis for the controllable preparation of PCEC with a certain molecular weight. Experiments show that with the increase of reaction concentration, reaction time and the CL/PEG ratio, the molecular weight of the PCEC increases; in addition, the effect of different molecular weight PEG macroinitiators on the molecular weight of PCEC is also studied. The results show that with the PEG molecular weight increases, the molecular weight of PCEC also shows an increasing trend.
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source American Institute of Physics:Jisc Collections:Transitional Journals Agreement 2021-23 (Reading list)
subjects Biocompatibility
Copolymerization
Molecular weight
Properties (attributes)
Reaction time
Ring opening polymerization
title Preparation and properties of biocompatible PCL-PEG-PCL(PCEC)
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