Preliminary evaluation of selected aptamers against hantaviruse

Hantavirus is a zoonotic, viral respiratory disease and is recent associated with human diseases that need a qualitative diagnosis method to promote a rational treatment as well as controlling the spread ability of the virus. Thus a early rational treatment is necessary in the outcome of the disease...

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Bibliographic Details
Main Authors: Valdez, E. C. N., Cortez, C. M., Oliveira, R. P. O. dos Santos, Vidal, S., Silva, D., de Lemos, E. R. S., Missailidis, S. S.
Format: Conference Proceeding
Language:English
Subjects:
Etiology
Proteins
Qualitative reasoning
Respiratory diseases
Viruses
Online Access:Get full text
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Summary:Hantavirus is a zoonotic, viral respiratory disease and is recent associated with human diseases that need a qualitative diagnosis method to promote a rational treatment as well as controlling the spread ability of the virus. Thus a early rational treatment is necessary in the outcome of the disease that on a identification etiological agent is essential. This paper shows results obtained from hantavirus aptamers interaction with the hantavirus protein, ANDES solution, throw fluorometric methods, that will assist in the determination of a secure path to aim an identification mechanism to identify the virus. The investigation revels that aptamer C2526 shows a high affinity binding with hantavirus protein, ANDES, being a promise reactive for recognizing assays.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.5138058