Secondary metabolites of Temu Putih (Curcuma zedoaria) rhizome

Curcuma zedoaria is a Zingiberacae plant commonly used as a traditional medicine. The objectives of this study were to isolate secondary metabolites from methanol fraction of rhizome and to identify the compounds using gas chromatography and mass spectrometry (GC-MS). The methanol extract yield was...

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Bibliographic Details
Main Authors: Syahbirin, G., Chahyaningtias, A. L., Radita, R., Ilmiawati, A.
Format: Conference Proceeding
Language:English
Subjects:
Chromatography
Diketones
Fractionation
Gas chromatography
Mass spectrometry
Metabolites
Methanol
Thin layer chromatography
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Summary:Curcuma zedoaria is a Zingiberacae plant commonly used as a traditional medicine. The objectives of this study were to isolate secondary metabolites from methanol fraction of rhizome and to identify the compounds using gas chromatography and mass spectrometry (GC-MS). The methanol extract yield was 20%. Fractionation using radial chromatography and preparative thin layer chromatography produced fractions 3A1 and 3A2 which were then analyzed using GC-MS. As many as 47 compounds were identified in fraction 3A1 including two predicted compounds, namely lippifoli-1(6)-en-4β-ol-5-one (I) and 2-benzo-thiazole-2-thiol (II). The compounds identified in fraction 3A2 were as many as 58, including compounds predicted as α-cyperone (III), mandolin A (IV), 1,6-dimethyl-9-(1-methylethylidene)-5,12-dioxatricyclododecan-8-one (V), and benzo[1,2-b:4,3-b’]dipyran-3,6-dione-2,2-dimethyl (VI). Based on the literature study, these compounds had never been reported to exist in zedoary.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0006477