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Synthesis of heterocycles on the base of trifluoroacetoacetate, methyl ketones and diamines
The three-component cyclization of ethyl trifluoroacetoacetate and 2-aminoethanol with 3-methyl-2-butanone in hexahydrooxazolo[3,2-a]pyridin-5-ones was studied. The reaction leads to a mixture of cis- and trans- diastereomers, the structures of which were investigated using 1H, 19F, 13C NMR spectros...
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Main Authors: | , , , |
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Format: | Conference Proceeding |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | The three-component cyclization of ethyl trifluoroacetoacetate and 2-aminoethanol with 3-methyl-2-butanone in hexahydrooxazolo[3,2-a]pyridin-5-ones was studied. The reaction leads to a mixture of cis- and trans- diastereomers, the structures of which were investigated using 1H, 19F, 13C NMR spectroscopy. |
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ISSN: | 0094-243X 1551-7616 |
DOI: | 10.1063/5.0069408 |