Evaluation of some inflammatory biomarkers and erythropoietine in rats with renal tubulointerstitial fibrosis

Determination of inflammatory biomarkers in sera of rats with renal tubulointerstitial fibrosis and evaluated the relation them with erythropoietin deficiency which causes anemia. Blood and histological samples collected from 80 male rats of albino BALB/c classified to sixty rats that were orally re...

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Bibliographic Details
Main Authors: Sultan, Ameer Radhi, Mohammed, Asma Hadi, Al-Kazazz, Fatin Fadhel Mohammed, Al Saedi, Ali Jasim Hashim
Format: Conference Proceeding
Language:English
Online Access:Get full text
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Summary:Determination of inflammatory biomarkers in sera of rats with renal tubulointerstitial fibrosis and evaluated the relation them with erythropoietin deficiency which causes anemia. Blood and histological samples collected from 80 male rats of albino BALB/c classified to sixty rats that were orally received with adenine at a concentration of 100 mg/kg to induce renal tubulointerstitial fibrosis, twenty rats as a control group. A highly significant increase in the serum levels of urea, creatinine, ferritin and Interleukin-6 and a highly significant decrease in blood hemoglobin and serum erythropoietin hormone in male rats with tubulointerstitial fibrosis compared with a control group (p
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0094936