Thermal noise calibration of functionalized cantilevers for force microscopy: Effects of the colloidal probe position

Colloidal probes are often used in force microscopy when the geometry of the tip–sample interaction should be well controlled. Their calibration requires an understanding of their mechanical response, which is very sensitive to the details of the force sensor consisting of a cantilever and the attac...

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Bibliographic Details
Published in:Journal of applied physics 2024-03, Vol.135 (9)
Main Authors: Archambault, Aubin, Crauste-Thibierge, Caroline, Bellon, Ludovic
Format: Article
Language:English
Subjects:
Calibration
Colloids
Mechanical analysis
Microscopy
Thermal noise
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Summary:Colloidal probes are often used in force microscopy when the geometry of the tip–sample interaction should be well controlled. Their calibration requires an understanding of their mechanical response, which is very sensitive to the details of the force sensor consisting of a cantilever and the attached colloid. We present some analytical models to describe the dynamics of the cantilever and its load positioned anywhere along its length. The thermal noise calibration of such probes is then studied from a practical point of view, leading to correction coefficients that can be applied in standard force microscope calibration routines. Experimental measurements of resonance frequencies and thermal noise profiles of raw and loaded cantilevers demonstrate the validity of the approach.
ISSN:0021-8979
1089-7550
DOI:10.1063/5.0189480