Breast dose reduction with organ-based, wide-angle tube current modulated CT

• Published in: Journal of medical imaging (Bellingham, Wash.) Wash.), 2017-07, Vol.4 (3), p.031208-031208
• Main Authors: Fu, Wanyi, Sturgeon, Gregory M, Agasthya, Greeshma, Segars, William Paul, Kapadia, Anuj J, Samei, Ehsan
• Format: Article
• Language: English
• Subjects: Special Section on Visions of Safety: s on Radiation Exposure
• ISSN: 2329-4302; 2329-4310
• DOI: 10.1117/1.JMI.4.3.031208

This study aimed to estimate the organ dose reduction potential for organ-dose-based tube current modulated (ODM) thoracic computed tomography (CT) with a wide dose reduction arc. Twenty-one computational anthropomorphic phantoms (XCAT) were used to create a virtual patient population with clinical anatomic variations. The phantoms were created based on patient images with normal anatomy (age range: 27 to 66 years, weight range: 52.0 to 105.8 kg). For each phantom, two breast tissue compositions were simulated: 50/50 and 20/80 (glandular-to-adipose ratio). A validated Monte Carlo program (PENELOPE, Universitat de Barcelona, Spain) was used to estimate the organ dose for standard tube current modulation (TCM) (SmartmA, GE Healthcare) and ODM (GE Healthcare) for a commercial CT scanner (Revolution, GE Healthcare) using a typical clinical thoracic CT protocol. Both organ dose and CTDIvol-to-organ dose conversion coefficients (h factors) were compared between TCM and ODM. ODM significantly reduced all radiosensitive organ doses (p