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The ability to perform high-resolution imaging of microvasculature and its oxygenation is very important in studying early tumor development. Toward this goal, we improved upon our excited state absorption (ESA)-based imaging technique to allow us to not only image hemoglobin directly but also diffe...

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Bibliographic Details
Main Authors: Fu, Dan, Matthews, Thomas E, Ye, Tong, Piletic, Ivan R, Warren, Warren S
Format: Conference Proceeding
Language:English
Subjects:
excited state absorption (ESA)
microvasculature imaging
multiphoton microscopy
oxygenation imaging
two-photon absorption
Online Access:Get full text
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Summary:The ability to perform high-resolution imaging of microvasculature and its oxygenation is very important in studying early tumor development. Toward this goal, we improved upon our excited state absorption (ESA)-based imaging technique to allow us to not only image hemoglobin directly but also differentiate between oxy- and deoxyhemoglobin in tissue. We demonstrate the separation of arterioles from venules in a live nude mouse ear using our imaging technique.
ISSN:1083-3668
1560-2281
DOI:10.1117/1.2968260