reply: Global methylation in eutherian hybrids: Genome evolution

The absence of global methylation changes in eutherian interspecific hybrids compared with their parents, observed by Roemer et al ., sharply contrasts with our own studies of interspecific hybrids between various species of kangaroo. We observed hybrid-specific undermethylation, retroelement activa...

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Bibliographic Details
Published in:Nature (London) 1999-09, Vol.401 (6749), p.132-132
Main Authors: O'Neill, Rachel J. Waugh, O'Neill, Michael J., Graves, Jennifer A. Marshall
Format: Article
Language:English
Subjects:
brief-communication
Humanities and Social Sciences
multidisciplinary
Science
Science (multidisciplinary)
Online Access:Get full text
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Summary:The absence of global methylation changes in eutherian interspecific hybrids compared with their parents, observed by Roemer et al ., sharply contrasts with our own studies of interspecific hybrids between various species of kangaroo. We observed hybrid-specific undermethylation, retroelement activation and genome remodelling 1 , and suggested that these events occurring together may bring about rapid karyotypic change.
ISSN:0028-0836
1476-4687
DOI:10.1038/43611