Loading…

Physical Activity and Sedentary Behaviour Thresholds for Secondary Prevention of Coronary Heart Disease: Morbidity Survival Tree Analysis

There are no diagnosis-specific guidelines for moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) for coronary heart disease (CHD). This study aimed to identify thresholds of MVPA and SB associated with cardiovascular events. This cohort study included individuals with CHD. M...

Full description

Saved in:
Bibliographic Details
Published in:Canadian journal of cardiology 2024-11
Main Authors: Lönn, Amanda, Niyonsenga, Theo, Carroll, Suzanne J., Bauman, Adrian, Davey, Rachel, Gallagher, Robyn, Freene, Nicole
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There are no diagnosis-specific guidelines for moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) for coronary heart disease (CHD). This study aimed to identify thresholds of MVPA and SB associated with cardiovascular events. This cohort study included individuals with CHD. MVPA and SB were self-reported, and health registries identified cardiovascular events in the years 2006-2022. Survival tree analyses identified thresholds of time associated with the risk of cardiovascular events. Thresholds were explored with the use of Cox regression models. There were 40,156 Australians, mean age 70 years, 62% men. Over a median 8.3 years, 3260 nonfatal cardiac events, 5161 total cardiac events, and 14,383 major adverse cardiovascular events (MACE) occurred. Thresholds for MVPA were 122 min/wk for nonfatal cardiac events and 94 min/wk for total cardiac events and MACE. Meeting MVPA thresholds was associated with an 18% lower risk for nonfatal cardiac events, 29% lower risk of total cardiac events, and 23% lower risk of MACE than not reaching the thresholds. Thresholds for SB were 4 and 10 h/d, respectively, for risk of total cardiac events and MACE. SB below thresholds was associated with a 14% lower risk of total cardiac events and an 18% lower risk of MACE. There were sex-specific thresholds for MVPA and SB. To lower cardiovascular event risk, identified MVPA thresholds were lower (94-122 min/wk) than the public health guidelines (150 min/wk) in individuals with CHD. The SB thresholds associated with a lower risk of total cardiac events and MACE varied from 4 to 10 h/d. Il n'existe pas de lignes directrices spécifiques au diagnostic concernant l'activité physique modérée à vigoureuse (APMV) et le comportement sédentaire (CS) pour la maladie coronarienne (MC). Cette étude visait à identifier les seuils d'APMV et de comportement sédentaire associés aux événements cardiovasculaires. Cette étude de cohorte a inclus des personnes atteintes de MC. L'APMV et le CS étaient autodéclarés et les registres de santé ont identifié les événements cardiovasculaires survenus entre 2006 et 2022. Des analyses avec un type d'arbre de décision appliqué aux données de survie ont permis d'identifier des seuils temporels associés au risque d'événements cardiovasculaires. Les seuils ont été explorés à l'aide de modèles de régression de Cox. L'étude comprenait 40 156 Australiens, d'un âge moyen de 70 ans, dont 62 % d'hommes. Sur une période médiane de 8,3 ans, 3 260
ISSN:0828-282X
1916-7075
1916-7075
DOI:10.1016/j.cjca.2024.11.025