Estimation of body fluids with bioimpedance spectroscopy: state of the art methods and proposal of novel methods

Determination of body fluids is a useful common practice in determination of disease mechanisms and treatments. Bioimpedance spectroscopy (BIS) methods are non-invasive, inexpensive and rapid alternatives to reference methods such as tracer dilution. However, they are indirect and their robustness a...

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Bibliographic Details
Published in:Physiological measurement 2015-10, Vol.36 (10), p.2171-2187
Main Authors: Buendia, R, Seoane, F, Lindecrantz, K, Bosaeus, I, Gil-Pita, R, Johannsson, G, Ellegård, L, Ward, L C
Format: Article
Language:English
Subjects:
bioimpedance
Biomedical Laboratory Science/Technology
Biomedicinsk laboratorievetenskap/teknologi
Body Composition
Body Fluids - chemistry
body fluids estimation
Clinical Medicine
Dielectric Spectroscopy - methods
Extracellular Space - chemistry
Humans
Intracellular Space - chemistry
Klinisk medicin
Medicin och hälsovetenskap
Människan i vården
Water - analysis
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Summary:Determination of body fluids is a useful common practice in determination of disease mechanisms and treatments. Bioimpedance spectroscopy (BIS) methods are non-invasive, inexpensive and rapid alternatives to reference methods such as tracer dilution. However, they are indirect and their robustness and validity are unclear. In this article, state of the art methods are reviewed, their drawbacks identified and new methods are proposed. All methods were tested on a clinical database of patients receiving growth hormone replacement therapy. Results indicated that most BIS methods are similarly accurate (e.g.  
ISSN:0967-3334
1361-6579
1361-6579
DOI:10.1088/0967-3334/36/10/2171