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A batch algorithm using iterative application of the Viterbi algorithm to track cells and construct cell lineages

Advances in microscope hardware in the last couple of decades have made it possible to acquire large data sets with image sequences of living cells grown in cell culture. This has led to a demand for automated ways of analyzing the acquired images. This article presents a new algorithm for tracking...

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Main Authors: Magnusson, K. E. G., Jalden, J.
Format: Conference Proceeding
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description Advances in microscope hardware in the last couple of decades have made it possible to acquire large data sets with image sequences of living cells grown in cell culture. This has led to a demand for automated ways of analyzing the acquired images. This article presents a new algorithm for tracking cells and constructing cell lineages in such image sequences. The algorithm uses information from the entire sequence to make local decisions about cell tracks and can therefore make more robust decisions than algorithms that process the data sequentially. It also incorporates image-based likelihoods of cell division and cell death into the tracking, without having to resort to separate detection algorithms or post processing of tracks. The algorithm consists of a scoring function to rank tracks and an iterative algorithm that searches for the highest scoring tracks, in a computationally efficient way, using the Viterbi algorithm.
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identifier ISSN: 1945-7928
ispartof 2012 9th IEEE International Symposium on Biomedical Imaging, 2012, p.382-385
issn 1945-7928
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language eng
recordid cdi_swepub_primary_oai_DiVA_org_kth_101503
source IEEE Electronic Library (IEL) Conference Proceedings
subjects Cell Tracking
Data Association
Dynamic Programming
Image segmentation
Image sequences
Microscopy
Multiple Target Tracking
Signal processing algorithms
Target tracking
Viterbi Algorithm
title A batch algorithm using iterative application of the Viterbi algorithm to track cells and construct cell lineages
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