Spatially well-defined carbohydrate nanoplatforms: synthesis, characterization and lectin interaction study

Two novel dodecasubstituted carbohydrate nanoplatforms based on molecular Borromean rings and dodecaamine cages have been prepared for use in evaluating the importance of the spatial distribution of carbohydrates in their interaction with lectins. The binding affinities of the glyconanoplatforms wer...

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Published in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (83), p.12326-12329
Main Authors: Timmer, B J J, Flos, M Abellán, Jørgensen, L Mønster, Proverbio, D, Altun, S, Ramström, O, Aastrup, T, Vincent, S P
Format: Article
Language:English
Subjects:
Binding
Cages
Carbohydrate Conformation
Carbohydrates
Carbohydrates - chemistry
Concanavalin A - chemistry
Lectins
Lectins - chemistry
Microbalances
Models, Molecular
Nanostructure
Nanotechnology - methods
Quartz Crystal Microbalance Techniques
Quartz crystals
Spatial distribution
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cited_by cdi_FETCH-LOGICAL-c394t-4fe827663bc5800449f744422f3f687da87f6e4771079017ab0c929df46917233
cites cdi_FETCH-LOGICAL-c394t-4fe827663bc5800449f744422f3f687da87f6e4771079017ab0c929df46917233
container_end_page 12329
container_issue 83
container_start_page 12326
container_title Chemical communications (Cambridge, England)
container_volume 52
creator Timmer, B J J
Flos, M Abellán
Jørgensen, L Mønster
Proverbio, D
Altun, S
Ramström, O
Aastrup, T
Vincent, S P
description Two novel dodecasubstituted carbohydrate nanoplatforms based on molecular Borromean rings and dodecaamine cages have been prepared for use in evaluating the importance of the spatial distribution of carbohydrates in their interaction with lectins. The binding affinities of the glyconanoplatforms were characterized using quartz crystal microbalance technology and compared with a monovalent reference and dodecaglycosylated fullerenes.
doi_str_mv 10.1039/c6cc06737a
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source Royal Society of Chemistry
subjects Binding
Cages
Carbohydrate Conformation
Carbohydrates
Carbohydrates - chemistry
Concanavalin A - chemistry
Lectins
Lectins - chemistry
Microbalances
Models, Molecular
Nanostructure
Nanotechnology - methods
Quartz Crystal Microbalance Techniques
Quartz crystals
Spatial distribution
title Spatially well-defined carbohydrate nanoplatforms: synthesis, characterization and lectin interaction study
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