Multivalent, bifunctional dendrimers prepared by click chemistry

Unsymmetrical dendrimers, containing both mannose binding units and coumarin fluorescent units, have been prepared using click chemistry and shown to be highly efficient, dual-purpose recognition/detection agents for the inhibition of hemagglutination.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2005-12 (46), p.5775-5777
Main Authors: Wu, Peng, Malkoch, Michael, Hunt, Jasmine N, Vestberg, Robert, Kaltgrad, Eiton, Finn, M G, Fokin, Valery V, Sharpless, K Barry, Hawker, Craig J
Format: Article
Language:English
Subjects:
Acetylene - chemistry
Dendrimers - chemistry
Hydrophobic and Hydrophilic Interactions
Molecular Structure
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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Summary:Unsymmetrical dendrimers, containing both mannose binding units and coumarin fluorescent units, have been prepared using click chemistry and shown to be highly efficient, dual-purpose recognition/detection agents for the inhibition of hemagglutination.
ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/b512021g