Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe

Synthetic routes have been developed for synthesis of potential metabolites of 25C-NBOMe and 25I-NBOMe. Nine potential metabolites have been synthesized, among which compounds 8 and 20a could be used as metabolite biomarkers of 25C-NBOMe and 20b of 25I-NBOMe in urinary detection at forensic laborato...

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Bibliographic Details
Published in:Tetrahedron 2017-11, Vol.73 (45), p.6393-6400
Main Authors: Wu, Xiongyu, Eriksson, Caroline, Wohlfarth, Ariane, Wallgren, Jakob, Kronstrand, Robert, Josefsson, Martin, Dahlén, Johan, Konradsson, Peter
Format: Article
Language:English
Subjects:
25C-NBOMe
25I-NBOMe
Biomarker
Metabolite
Urinary detection
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Summary:Synthetic routes have been developed for synthesis of potential metabolites of 25C-NBOMe and 25I-NBOMe. Nine potential metabolites have been synthesized, among which compounds 8 and 20a could be used as metabolite biomarkers of 25C-NBOMe and 20b of 25I-NBOMe in urinary detection at forensic laboratories to prove intake. [Display omitted]
ISSN:0040-4020
1464-5416
1464-5416
DOI:10.1016/j.tet.2017.09.024