Clinical factors associated with the recurrence of central giant cell lesions

Central giant cell lesion of the jaws (CGCLJ) is a destructive condition that shows a varied and unpredictable biological behaviour. In the present study, we aimed to evaluate factors associated with the recurrence of CGCLJ. Based on the data of a previous systematic review of 2270 cases of CGCLJ, w...

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Published in:Journal of oral pathology & medicine 2019-10, Vol.48 (9), p.799-802
Main Authors: Chrcanovic, Bruno Ramos, Gomes, Carolina Cavaliéri, Santos, Thiago Rezende, Abreu, Mauro Henrique Nogueira Guimarães, Gomez, Ricardo Santiago
Format: Article
Language:English
Subjects:
bone disease
central giant cell granuloma
Central giant cell lesion
clinical features
Cortical bone
Curettage
Dentistry
Enucleation
Giant Cells
Granuloma, Giant Cell
Granulomas
Humans
Jaw
Mandible
Maxilla
Pain
Recurrence
recurrence rate
Root resorption
Teeth
treatment
Tumors
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Summary:Central giant cell lesion of the jaws (CGCLJ) is a destructive condition that shows a varied and unpredictable biological behaviour. In the present study, we aimed to evaluate factors associated with the recurrence of CGCLJ. Based on the data of a previous systematic review of 2270 cases of CGCLJ, we used the multiple imputation to deal with the missing data. The dependent variable was the recurrence after the first treatment (yes/no). The dichotomic covariates were sex, upper or lower jaw location, size (up to or larger than 4 cm), pain, cortical bone perforation (yes/no), locularity (uni‐/multilocular), tooth displacement (yes/no), treatment type (curettage or enucleation) and root resorption (yes/no). The final logistic model indicated that the tumours associated with tooth displacement, root resorption and treated with curettage had a more significant chance of recurrence. In conclusion, our study suggests that tooth displacement, root resorption and the type of treatment are potentially useful in the future construction of an algorithm for patient's treatment.
ISSN:0904-2512
1600-0714
1600-0714
DOI:10.1111/jop.12937