Erythrocytosis in children and adolescents-classification, characterization, and consensus recommendations for the diagnostic approach

ABSTRACT During recent years, the increasing knowledge of genetic and physiological changes in polycythemia vera (PV) and of different types of congenital erythrocytosis has led to fundamental changes in recommendations for the diagnostic approach to patients with erythrocytosis. Although widely acc...

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Bibliographic Details
Published in:Pediatric blood & cancer 2013-11, Vol.60 (11), p.1734-1738
Main Authors: Cario, Holger, Frances McMullin, Mary, Bento, Celeste, Pospisilova, Dagmar, Percy, Melanie J., Hussein, Kais, Schwarz, Jiri, Åström, Maria, Hermouet, Sylvie
Format: Article
Language:English
Subjects:
Adolescent
adolescents
Adult
Algorithms
Child
children
congenital erythrocytosis
diagnostic algorithm
Hematology
Humans
Oncology
Pediatrics
Polycythemia - classification
Polycythemia - diagnosis
polycythemia vera
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Summary:ABSTRACT During recent years, the increasing knowledge of genetic and physiological changes in polycythemia vera (PV) and of different types of congenital erythrocytosis has led to fundamental changes in recommendations for the diagnostic approach to patients with erythrocytosis. Although widely accepted for adult patients this approach may not be appropriate with regard to children and adolescents affected by erythrocytosis. The “congenital erythrocytosis” working group established within the framework of the MPN&MPNr‐EuroNet (COST action BM0902) addressed this question in a consensus finding process and developed a specific algorithm for the diagnosis of erythrocytosis in childhood and adolescence which is presented here. Pediatr Blood Cancer 2013;60:1734–1738. © 2013 Wiley Periodicals, Inc.
ISSN:1545-5009
1545-5017
1545-5017
DOI:10.1002/pbc.24625