ULTRASOUND-MEDIATED THREE-COMPONENT REACTION ON-WATER PROTOCOL FOR THE SYNTHESIS OF NOVEL MONO- AND BIS-1,3-THIAZIN-4-ONE DERIVATIVES

Green synthetic and catalyst-free strategy towards the synthesis of novel mono- and bis-1,3-thiazin-4-one scaffolds through a one pot, reaction of carbon disulfide, monoacetylenic esters and amines under ultrasonication has been reported. The merits of this protocol comprise no need for tedious work...

Full description

Saved in:
Bibliographic Details
Published in:Heterocycles 2017, Vol.94 (8), p.1439
Main Authors: Arafa, Wael A. A., Mohamed, Ashraf M., Abdel-Magied, Ahmed F.
Format: Article
Language:English
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Green synthetic and catalyst-free strategy towards the synthesis of novel mono- and bis-1,3-thiazin-4-one scaffolds through a one pot, reaction of carbon disulfide, monoacetylenic esters and amines under ultrasonication has been reported. The merits of this protocol comprise no need for tedious workup steps and afforded the desired products in excellent yields make this synthetic protocol more efficient and worthy of further attentiveness. Moreover, the method exhibited excellent score in a number of green metrics.
ISSN:1881-0942
0385-5414
DOI:10.3987/COM-17-13726