Local olfactory interneurons provide the basis for neurochemical regionalization of olfactory glomeruli in crustaceans

The primary olfactory centers of metazoans as diverse as arthropods and mammals consist of an array of fields of dense synaptic neuropil, the olfactory glomeruli. However, the neurochemical structure of crustacean olfactory glomeruli is largely understudied when compared to the insects. We analyzed...

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Bibliographic Details
Published in:Journal of comparative neurology (1911) 2022-06, Vol.530 (9), p.1399-1422
Main Authors: Harzsch, Steffen, Dircksen, Heinrich, Hansson, Bill S.
Format: Article
Language:English
Subjects:
Animals
Anomura
Coenobita clypeatus
Crustacea
Crustaceans
Immunohistochemistry
Information processing
Inhibition
Interneurons
Mammals
Neuropeptides
Neuropil
Neuropil - metabolism
Olfaction
Olfactory Bulb
Olfactory glomeruli
olfactory interneurons
Olfactory Pathways - metabolism
Olfactory Receptor Neurons
olfactory system
Pagurus bernhardus
Presynapse
Sensory neurons
Serotonin
zoologi
Zoology
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Summary:The primary olfactory centers of metazoans as diverse as arthropods and mammals consist of an array of fields of dense synaptic neuropil, the olfactory glomeruli. However, the neurochemical structure of crustacean olfactory glomeruli is largely understudied when compared to the insects. We analyzed the glomerular architecture in selected species of hermit crabs using immunohistochemistry against presynaptic proteins, the neuropeptides orcokinin, RFamide and allatostatin, and the biogenic amine serotonin. Our study reveals an unexpected level of structural complexity, unmatched by what is found in the insect olfactory glomeruli. Peptidergic and aminergic interneurons provide the structural basis for a regionalization of the crustacean glomeruli into longitudinal and concentric compartments. Our data suggest that local olfactory interneurons take a central computational role in modulating the information transfer from olfactory sensory neurons to projection neurons within the glomeruli. Furthermore, we found yet unknown neuronal elements mediating lateral inhibitory interactions across the glomerular array that may play a central role in modulating the transfer of sensory input to the output neurons through presynaptic inhibition. Our study is another step in understanding the function of crustacean olfactory glomeruli as highly complex units of local olfactory processing. Central olfactory pathway in the brain of the hermit crabs Pagurus bernhardus and Coenobita clypeatus: summary of glomerular structure and neurochemistry.
ISSN:0021-9967
1096-9861
1096-9861
DOI:10.1002/cne.25283