Nanodosimetry in a (12)C ion beam using Monte Carlo simulations

The dose-mean lineal energy, (y) over bar (D), has been calculated in water for irradiation with (12)C ions with initial energies 290 MeV/u. The y, was evaluated from the energy distributions of carbon and secondary boron ions, and from their energy-dependent pp-values. The energy distributions were...

Full description

Saved in:
Bibliographic Details
Published in:Radiation measurements 2010-12, Vol.45 (10), p.1238
Main Authors: Hultqvist, Martha, Lillhok, J-E, Lindborg, L., Gudowska, Irena, Nikjoo, H.
Format: Article
Language:English
Subjects:
Carbon ion radiotherapy
Microdosimetry
Monte Carlo simulation
Nanodosimetry
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The dose-mean lineal energy, (y) over bar (D), has been calculated in water for irradiation with (12)C ions with initial energies 290 MeV/u. The y, was evaluated from the energy distributions of carbon and secondary boron ions, and from their energy-dependent pp-values. The energy distributions were obtained from simulations with the Monte Carlo code SHIELD-HIT07 and the energy-dependent (y) over bar (D)-values were obtained from ion-track simulations with PITS99 coupled with the electron transport code KURBUC. The ratio of the (y) over bar (D)-value determined in the vicinity of the Bragg peak to that calculated in a reference (60)Co gamma beam was compared with the corresponding ratio of alpha-values from the linear-quadratic model used in fractionated radiotherapy, showing a good correlation for an object size of around 10 nm.
ISSN:1350-4487
1879-0925
DOI:10.1016/j.radmeas.2010.05.033