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The impact of adjusted work conditions and disease-modifying drugs on work ability in multiple sclerosis
Background: Multiple sclerosis (MS) is a neurological disorder that causes significantly reduced ability to work, and the Expanded Disability Status Scale (EDSS) is one of the main predictors for reduced work ability. Objectives: To investigate how work requirements, flexible work conditions and dis...
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| Published in: | Multiple sclerosis 2017-07, Vol.23 (8), p.1137-1147 |
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| Main Authors: | , , , , , , |
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| cites | cdi_FETCH-LOGICAL-c511t-290cc8b6de61df2afbf2324d18a8ef37d5a1cee2fcf9b5b8aa9ff9611d34610f3 |
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| container_title | Multiple sclerosis |
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| creator | Wickström, Anne Fagerström, Maria Wickström, Lucas Granåsen, Gabriel Dahle, Charlotte Vrethem, Magnus Sundström, Peter |
| description | Background:
Multiple sclerosis (MS) is a neurological disorder that causes significantly reduced ability to work, and the Expanded Disability Status Scale (EDSS) is one of the main predictors for reduced work ability.
Objectives:
To investigate how work requirements, flexible work conditions and disease-modifying drugs (DMDs) influence the work ability in relation to different EDSS grades in two MS populations.
Methods:
Work ability was studied in two MS populations: one in the southern and one in the northern part of Sweden, both demographically similar. In the latter population, more active work-promoting interventions have been practised and second-generation DMDs have been widely used from the onset of disease for several years.
Results:
The proportion of MS patients who participated in the workforce or studied was significantly higher in the northern compared with the southern population (p |
| doi_str_mv | 10.1177/1352458516671818 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_swepu</sourceid><recordid>TN_cdi_swepub_primary_oai_DiVA_org_umu_127490</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1352458516671818</sage_id><sourcerecordid>1835489236</sourcerecordid><originalsourceid>FETCH-LOGICAL-c511t-290cc8b6de61df2afbf2324d18a8ef37d5a1cee2fcf9b5b8aa9ff9611d34610f3</originalsourceid><addsrcrecordid>eNqNkctrFTEUxoMotlb3riTgxs1oTjKZJMtSn1BwU92GTB63uc5MxmRCuf-9KbeWUhBcnQPnd77z-BB6DeQ9gBAfgHHac8lhGARIkE_QKfRCdEQJ8rTlrdzd1k_Qi1L2hBAhGH-OTqgQXCrOT9H11bXHcV6N3XAK2Lh9LZt3-CblX9imxcUtpqVgszjsYvGm-G5OLoZDXHbY5borOC1H3IxxitsBxwXPddriOnlc7ORzKrG8RM-CmYp_dRfP0I_Pn64uvnaX3798uzi_7CwH2DqqiLVyHJwfwAVqwhgoo70DaaQPTDhuwHpPgw1q5KM0RoWgBgDH-gFIYGeoO-qWG7_WUa85ziYfdDJRf4w_z3XKO13nqoGKXpH_46fYeKbowBr_7sivOf2uvmx6jsX6aTKLT7VokIz3UlE2NPTtI3Sfal7a9RoUENlLIaFR5EjZ9qeSfbhfAYi-dVk_drm1vLkTruPs3X3DX1sfHGV2_sHUfwn-AeYbsPY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1910848781</pqid></control><display><type>article</type><title>The impact of adjusted work conditions and disease-modifying drugs on work ability in multiple sclerosis</title><source>SAGE Journals</source><creator>Wickström, Anne ; Fagerström, Maria ; Wickström, Lucas ; Granåsen, Gabriel ; Dahle, Charlotte ; Vrethem, Magnus ; Sundström, Peter</creator><creatorcontrib>Wickström, Anne ; Fagerström, Maria ; Wickström, Lucas ; Granåsen, Gabriel ; Dahle, Charlotte ; Vrethem, Magnus ; Sundström, Peter</creatorcontrib><description>Background:
Multiple sclerosis (MS) is a neurological disorder that causes significantly reduced ability to work, and the Expanded Disability Status Scale (EDSS) is one of the main predictors for reduced work ability.
Objectives:
To investigate how work requirements, flexible work conditions and disease-modifying drugs (DMDs) influence the work ability in relation to different EDSS grades in two MS populations.
Methods:
Work ability was studied in two MS populations: one in the southern and one in the northern part of Sweden, both demographically similar. In the latter population, more active work-promoting interventions have been practised and second-generation DMDs have been widely used from the onset of disease for several years.
Results:
The proportion of MS patients who participated in the workforce or studied was significantly higher in the northern compared with the southern population (p < 0.001). The employees in the northern population had significantly lower requirements, greater adapted work conditions and were able to work more hours per week. Higher EDSS was associated with lower reduction in number of worked hours per week in the northern population (p = 0.042).
Conclusion:
Our data indicated that treatment strategy and adjusted work conditions have impact on work ability in MS.</description><identifier>ISSN: 1352-4585</identifier><identifier>ISSN: 1477-0970</identifier><identifier>EISSN: 1477-0970</identifier><identifier>DOI: 10.1177/1352458516671818</identifier><identifier>PMID: 27758955</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>adjusted work conditions ; Adolescent ; Adult ; disease-modifying drugs ; Female ; Humans ; Immunosuppressive Agents - therapeutic use ; Job satisfaction ; Male ; Middle Aged ; Multiple sclerosis ; Multiple Sclerosis - drug therapy ; Population ; Sweden ; Treatment Outcome ; Work ; Work Ability Questionnaire – Multiple Sclerosis ; Work environment ; work requirements ; working ability ; Working conditions ; Young Adult</subject><ispartof>Multiple sclerosis, 2017-07, Vol.23 (8), p.1137-1147</ispartof><rights>The Author(s), 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c511t-290cc8b6de61df2afbf2324d18a8ef37d5a1cee2fcf9b5b8aa9ff9611d34610f3</citedby><cites>FETCH-LOGICAL-c511t-290cc8b6de61df2afbf2324d18a8ef37d5a1cee2fcf9b5b8aa9ff9611d34610f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27758955$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-139263$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-127490$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Wickström, Anne</creatorcontrib><creatorcontrib>Fagerström, Maria</creatorcontrib><creatorcontrib>Wickström, Lucas</creatorcontrib><creatorcontrib>Granåsen, Gabriel</creatorcontrib><creatorcontrib>Dahle, Charlotte</creatorcontrib><creatorcontrib>Vrethem, Magnus</creatorcontrib><creatorcontrib>Sundström, Peter</creatorcontrib><title>The impact of adjusted work conditions and disease-modifying drugs on work ability in multiple sclerosis</title><title>Multiple sclerosis</title><addtitle>Mult Scler</addtitle><description>Background:
Multiple sclerosis (MS) is a neurological disorder that causes significantly reduced ability to work, and the Expanded Disability Status Scale (EDSS) is one of the main predictors for reduced work ability.
Objectives:
To investigate how work requirements, flexible work conditions and disease-modifying drugs (DMDs) influence the work ability in relation to different EDSS grades in two MS populations.
Methods:
Work ability was studied in two MS populations: one in the southern and one in the northern part of Sweden, both demographically similar. In the latter population, more active work-promoting interventions have been practised and second-generation DMDs have been widely used from the onset of disease for several years.
Results:
The proportion of MS patients who participated in the workforce or studied was significantly higher in the northern compared with the southern population (p < 0.001). The employees in the northern population had significantly lower requirements, greater adapted work conditions and were able to work more hours per week. Higher EDSS was associated with lower reduction in number of worked hours per week in the northern population (p = 0.042).
Conclusion:
Our data indicated that treatment strategy and adjusted work conditions have impact on work ability in MS.</description><subject>adjusted work conditions</subject><subject>Adolescent</subject><subject>Adult</subject><subject>disease-modifying drugs</subject><subject>Female</subject><subject>Humans</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Job satisfaction</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multiple sclerosis</subject><subject>Multiple Sclerosis - drug therapy</subject><subject>Population</subject><subject>Sweden</subject><subject>Treatment Outcome</subject><subject>Work</subject><subject>Work Ability Questionnaire – Multiple Sclerosis</subject><subject>Work environment</subject><subject>work requirements</subject><subject>working ability</subject><subject>Working conditions</subject><subject>Young Adult</subject><issn>1352-4585</issn><issn>1477-0970</issn><issn>1477-0970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNqNkctrFTEUxoMotlb3riTgxs1oTjKZJMtSn1BwU92GTB63uc5MxmRCuf-9KbeWUhBcnQPnd77z-BB6DeQ9gBAfgHHac8lhGARIkE_QKfRCdEQJ8rTlrdzd1k_Qi1L2hBAhGH-OTqgQXCrOT9H11bXHcV6N3XAK2Lh9LZt3-CblX9imxcUtpqVgszjsYvGm-G5OLoZDXHbY5borOC1H3IxxitsBxwXPddriOnlc7ORzKrG8RM-CmYp_dRfP0I_Pn64uvnaX3798uzi_7CwH2DqqiLVyHJwfwAVqwhgoo70DaaQPTDhuwHpPgw1q5KM0RoWgBgDH-gFIYGeoO-qWG7_WUa85ziYfdDJRf4w_z3XKO13nqoGKXpH_46fYeKbowBr_7sivOf2uvmx6jsX6aTKLT7VokIz3UlE2NPTtI3Sfal7a9RoUENlLIaFR5EjZ9qeSfbhfAYi-dVk_drm1vLkTruPs3X3DX1sfHGV2_sHUfwn-AeYbsPY</recordid><startdate>20170701</startdate><enddate>20170701</enddate><creator>Wickström, Anne</creator><creator>Fagerström, Maria</creator><creator>Wickström, Lucas</creator><creator>Granåsen, Gabriel</creator><creator>Dahle, Charlotte</creator><creator>Vrethem, Magnus</creator><creator>Sundström, Peter</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>DG8</scope><scope>D93</scope></search><sort><creationdate>20170701</creationdate><title>The impact of adjusted work conditions and disease-modifying drugs on work ability in multiple sclerosis</title><author>Wickström, Anne ; Fagerström, Maria ; Wickström, Lucas ; Granåsen, Gabriel ; Dahle, Charlotte ; Vrethem, Magnus ; Sundström, Peter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c511t-290cc8b6de61df2afbf2324d18a8ef37d5a1cee2fcf9b5b8aa9ff9611d34610f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>adjusted work conditions</topic><topic>Adolescent</topic><topic>Adult</topic><topic>disease-modifying drugs</topic><topic>Female</topic><topic>Humans</topic><topic>Immunosuppressive Agents - therapeutic use</topic><topic>Job satisfaction</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multiple sclerosis</topic><topic>Multiple Sclerosis - drug therapy</topic><topic>Population</topic><topic>Sweden</topic><topic>Treatment Outcome</topic><topic>Work</topic><topic>Work Ability Questionnaire – Multiple Sclerosis</topic><topic>Work environment</topic><topic>work requirements</topic><topic>working ability</topic><topic>Working conditions</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wickström, Anne</creatorcontrib><creatorcontrib>Fagerström, Maria</creatorcontrib><creatorcontrib>Wickström, Lucas</creatorcontrib><creatorcontrib>Granåsen, Gabriel</creatorcontrib><creatorcontrib>Dahle, Charlotte</creatorcontrib><creatorcontrib>Vrethem, Magnus</creatorcontrib><creatorcontrib>Sundström, Peter</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Linköpings universitet</collection><collection>SWEPUB Umeå universitet</collection><jtitle>Multiple sclerosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wickström, Anne</au><au>Fagerström, Maria</au><au>Wickström, Lucas</au><au>Granåsen, Gabriel</au><au>Dahle, Charlotte</au><au>Vrethem, Magnus</au><au>Sundström, Peter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The impact of adjusted work conditions and disease-modifying drugs on work ability in multiple sclerosis</atitle><jtitle>Multiple sclerosis</jtitle><addtitle>Mult Scler</addtitle><date>2017-07-01</date><risdate>2017</risdate><volume>23</volume><issue>8</issue><spage>1137</spage><epage>1147</epage><pages>1137-1147</pages><issn>1352-4585</issn><issn>1477-0970</issn><eissn>1477-0970</eissn><abstract>Background:
Multiple sclerosis (MS) is a neurological disorder that causes significantly reduced ability to work, and the Expanded Disability Status Scale (EDSS) is one of the main predictors for reduced work ability.
Objectives:
To investigate how work requirements, flexible work conditions and disease-modifying drugs (DMDs) influence the work ability in relation to different EDSS grades in two MS populations.
Methods:
Work ability was studied in two MS populations: one in the southern and one in the northern part of Sweden, both demographically similar. In the latter population, more active work-promoting interventions have been practised and second-generation DMDs have been widely used from the onset of disease for several years.
Results:
The proportion of MS patients who participated in the workforce or studied was significantly higher in the northern compared with the southern population (p < 0.001). The employees in the northern population had significantly lower requirements, greater adapted work conditions and were able to work more hours per week. Higher EDSS was associated with lower reduction in number of worked hours per week in the northern population (p = 0.042).
Conclusion:
Our data indicated that treatment strategy and adjusted work conditions have impact on work ability in MS.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>27758955</pmid><doi>10.1177/1352458516671818</doi><tpages>11</tpages></addata></record> |
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| ispartof | Multiple sclerosis, 2017-07, Vol.23 (8), p.1137-1147 |
| issn | 1352-4585 1477-0970 1477-0970 |
| language | eng |
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| source | SAGE Journals |
| subjects | adjusted work conditions Adolescent Adult disease-modifying drugs Female Humans Immunosuppressive Agents - therapeutic use Job satisfaction Male Middle Aged Multiple sclerosis Multiple Sclerosis - drug therapy Population Sweden Treatment Outcome Work Work Ability Questionnaire – Multiple Sclerosis Work environment work requirements working ability Working conditions Young Adult |
| title | The impact of adjusted work conditions and disease-modifying drugs on work ability in multiple sclerosis |
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