Associations of Sarcopenia and Its Components with Bone Structure and Incident Falls in Swedish Older Adults

The aim of this study was to compare bone structure parameters and likelihood of falls across European Working Group on Sarcopenia in Older People (EWGSOP2) sarcopenia categories. 3334 Swedish 70-year olds had appendicular lean mass (normalized to height; ALMHt), lumbar spine and total hip areal BMD...

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Bibliographic Details
Published in:Calcified tissue international 2019-07, Vol.105 (1), p.26-36
Main Authors: Scott, David, Johansson, Jonas, McMillan, Lachlan B., Ebeling, Peter R., Nordstrom, Peter, Nordstrom, Anna
Format: Article
Language:English
Subjects:
Amputation
Biochemistry
Biomedical and Life Sciences
Bone
Bone mineral density
Cell Biology
Computed tomography
Dual energy X-ray absorptiometry
Endocrinology
Falls
Hip
Life Sciences
Medical disciplines: 700
Medisinske Fag: 700
Muscle
Older adults
Older people
Original Research
Orthopedics
Osteoporosis
Radius
Sarcopenia
Spine (lumbar)
Tibia
VDP
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Summary:The aim of this study was to compare bone structure parameters and likelihood of falls across European Working Group on Sarcopenia in Older People (EWGSOP2) sarcopenia categories. 3334 Swedish 70-year olds had appendicular lean mass (normalized to height; ALMHt), lumbar spine and total hip areal BMD (aBMD) estimated by dual-energy X-ray absorptiometry. Volumetric BMD (vBMD) and structure at the distal and proximal tibia and radius were estimated by peripheral quantitative computed tomography. Hand grip strength and timed up-and-go were assessed, and sarcopenia was defined according to EWGSOP2 criteria. Incident falls were self-reported 6 and 12 months after baseline. Only 0.8% and 1.0% of participants had probable and confirmed sarcopenia, respectively. Almost one-third of participants with confirmed sarcopenia reported incident falls, compared with 20% for probable sarcopenia and 14% without sarcopenia ( P  = 0.025). Participants with confirmed sarcopenia had poorer bone parameters (all P  
ISSN:0171-967X
1432-0827
1432-0827
DOI:10.1007/s00223-019-00540-1