Detection and characterization of immunoconglutinins in patients with systemic lupus erythematosus (SLE): serial analysis in relation to disease course

SUMMARY The levels of IgA, IgG and IgM immunoconglutinins (IK) were assessed in sera from 20 patients with SLE which were followed for 8‐month periods. At the time of the exacerbation, IgG IKs were significantly increased to 226 ± 90 arbitrary units (mean ± s.e.m.) compared with both the minimum val...

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Bibliographic Details
Published in:Clinical and experimental immunology 1992-11, Vol.90 (2), p.251-255
Main Authors: NILSSON, B., EKDAHL, K. NILSSON, SJÖHOLM, A., NILSSON, U. R., STURFELT, G.
Format: Article
Language:English
Subjects:
Antibody Specificity
Autoantibodies - immunology
complement activation
Complement C3 - immunology
Complement C3d - metabolism
Complement C4 - immunology
Humans
IgG
IgM
Immunoconglutinins
Immunoglobulin A - immunology
Immunoglobulin G - immunology
Immunoglobulin Isotypes - immunology
Immunoglobulin M - immunology
Immunoglobulins - immunology
Lupus Erythematosus, Systemic - immunology
Prospective Studies
systemic lupus erythematosus
Time Factors
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Summary:SUMMARY The levels of IgA, IgG and IgM immunoconglutinins (IK) were assessed in sera from 20 patients with SLE which were followed for 8‐month periods. At the time of the exacerbation, IgG IKs were significantly increased to 226 ± 90 arbitrary units (mean ± s.e.m.) compared with both the minimum value of 75 ± 28 in the SLE patients and with 31 ± 2 in healthy controls (P
ISSN:0009-9104
1365-2249
1365-2249
DOI:10.1111/j.1365-2249.1992.tb07937.x