Simultaneous monitoring of intratidal compliance and resistance in mechanically ventilated piglets: A feasibility study in two different study groups

Highlights • Intratidal resistance–volume profiles change in a characteristic way depending on PEEP, tidal volume and the underlying mechanical properties of the lung. • In healthy lungs, intratidal resistance–volume profiles decline linearly. • A curved intratidal resistance decline might indicate...

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Bibliographic Details
Published in:Respiratory physiology & neurobiology 2015-12, Vol.219, p.36-42
Main Authors: Buehler, Sarah, Schumann, Stefan, Vimláti, László, Lichtwarck-Aschoff, Michael, Guttmann, Josef
Format: Article
Language:English
Subjects:
Airway Resistance
Animals
Compliance
Feasibility Studies
Lung Compliance
Mechanical ventilation
Medical Education
Monitoring, Physiologic - methods
PEEP
Positive-Pressure Respiration - methods
Pulmonary/Respiratory
Resistance
Respiratory Mechanics
Swine
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Summary:Highlights • Intratidal resistance–volume profiles change in a characteristic way depending on PEEP, tidal volume and the underlying mechanical properties of the lung. • In healthy lungs, intratidal resistance–volume profiles decline linearly. • A curved intratidal resistance decline might indicate pathological changes in the underlying mechanical lung properties. • Intratidal resistance–volume profiles might help guiding a lung protective ventilation setting.
ISSN:1569-9048
1878-1519
1878-1519
DOI:10.1016/j.resp.2015.08.001