Microwave-Accelerated Homogeneous Catalysis in Organic Chemistry

The efficiency of microwave flash heating in accelerating organic transformations (reaction times reduced from days and hours to minutes and seconds) has recently been proven in several different fields of organic chemistry. This specific account mainly summarizes our own experiences in developing r...

Full description

Saved in:
Bibliographic Details
Published in:Accounts of chemical research 2002-09, Vol.35 (9), p.717-727
Main Authors: Larhed, Mats, Moberg, Christina, Hallberg, Anders
Format: Article
Language:English
Subjects:
aryl
asymmetric allylic alkylation
c-n
Catalysis
Chemistry, Organic - methods
Chemistry, Organic - standards
convenient
cross-coupling reactions
Environmental Pollution - prevention & control
Heating
heck arylation
high-speed chemistry
hiv-1 protease inhibitors
irradiation
Kinetics
Microwaves
Molecular Structure
palladium
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The efficiency of microwave flash heating in accelerating organic transformations (reaction times reduced from days and hours to minutes and seconds) has recently been proven in several different fields of organic chemistry. This specific account mainly summarizes our own experiences in developing rapid, robust, and selective microwave-assisted transition metal-catalyzed homogeneous reactions. Applications include selective Heck couplings, cross-couplings, and asymmetric substitutions. The science of green chemistry was developed to meet the increasing demand for environmentally benign chemical processes. We believe the combination of metal catalysis and microwave heating will be of importance in the search for green laboratory-scale synthesis.
ISSN:0001-4842
1520-4898
1520-4898
DOI:10.1021/ar010074v