Reassuringly low carriage of enteropathogens among healthy Swedish children in day care centres

Abstract Objectives Infectious gastroenteritis is one of the most common diseases among children and has a considerable impact on health and socio-economy. Day care centres are high-risk environments for infections. The aim of this study was to investigate if asymptomatic preschool children constitu...

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Bibliographic Details
Published in:Public health (London) 2016-11, Vol.140, p.221-227
Main Authors: Kaarme, J, Hickman, R.A, Nevéus, T, Blomberg, J, Öhrmalm, C
Format: Article
Language:English
Subjects:
Adenoviridae - isolation & purification
Campylobacter
Campylobacter - isolation & purification
Carriage
Carrier State - epidemiology
Chemical analysis
Child Day Care Centers
Child, Preschool
Children
Childrens health
Day care centers
Day care centres (DCCs)
Diapers
Disease Reservoirs
Enteropathogens
Feces - microbiology
Feces - virology
Fluorescence
Gastroenteritis
Gastroenteritis - epidemiology
Health care
Health risks
High risk
Humans
Impact analysis
Infant
Infectious Disease
Internal Medicine
Molecular chains
Norovirus - isolation & purification
Pathogens
Polymerase Chain Reaction
Preschool
Preschool children
Prevalence
Risk Assessment
Risk factors
Sweden - epidemiology
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Summary:Abstract Objectives Infectious gastroenteritis is one of the most common diseases among children and has a considerable impact on health and socio-economy. Day care centres are high-risk environments for infections. The aim of this study was to investigate if asymptomatic preschool children constitute a reservoir for potential enteropathogens. Study design In total, 438 individual diapers were collected from day care centres in Uppsala, Sweden, during spring and autumn, and molecular techniques were used to estimate the prevalence of asymptomatic carriage of multiple enteropathogens. Methods Faecal samples were analysed with multiplex polymerase chain reaction (PCR) (xTAG® Gastrointestinal Pathogen Panel; Luminex Corporation, Toronto, Canada) targeting 21 different pathogens. Samples with a median fluorescence intensity above threshold were re-analysed with a second PCR assay. Results Sixteen of the 438 samples were positive for enteropathogens, 1.6% for enteric adenovirus, 0.7% for Campylobacter spp., and 0.7% for norovirus. Conclusions Preschool children in Uppsala constitute a limited reservoir for potential enteropathogens.
ISSN:0033-3506
1476-5616
1476-5616
DOI:10.1016/j.puhe.2016.05.011