A novel community driven software for functional enrichment analysis of extracellular vesicles data

Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fai...

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Bibliographic Details
Published in:Journal of extracellular vesicles 2017, Vol.6 (1), p.1321455-n/a
Main Authors: Pathan, Mohashin, Keerthikumar, Shivakumar, Chisanga, David, Alessandro, Riccardo, Ang, Ching-Seng, Askenase, Philip, Batagov, Arsen O., Benito-Martin, Alberto, Camussi, Giovanni, Clayton, Aled, Collino, Federica, Di Vizio, Dolores, Falcon-Perez, Juan Manuel, Fonseca, Pedro, Fonseka, Pamali, Fontana, Simona, Gho, Yong Song, Hendrix, An, Hoen, Esther Nolte-'t, Iraci, Nunzio, Kastaniegaard, Kenneth, Kislinger, Thomas, Kowal, Joanna, Kurochkin, Igor V., Leonardi, Tommaso, Liang, Yaxuan, Llorente, Alicia, Lunavat, Taral R., Maji, Sayantan, Monteleone, Francesca, Øverbye, Anders, Panaretakis, Theocharis, Patel, Tushar, Peinado, Héctor, Pluchino, Stefano, Principe, Simona, Ronquist, Goran, Royo, Felix, Sahoo, Susmita, Spinelli, Cristiana, Stensballe, Allan, Théry, Clotilde, van Herwijnen, Martijn J.C., Wauben, Marca, Welton, Joanne L., Zhao, Kening, Mathivanan, Suresh
Format: Article
Language:English
Subjects:
Biochemistry
Bioinformatics
cancer
Cell Biology
Computer programs
Data analysis
Data processing
Datasets
Extracellular vesicles
FunRich
Gene set enrichment analysis
Genes
Genomes
Laboratories
Medical Biotechnology
Medicin och hälsovetenskap
Medicinsk bioteknologi
Open access
Proteins
Proteomics
Researchers
Short Communication
Social research
Software
Software development
Software upgrading
Software utilities
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Summary:Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture "what the community needs in a tool". Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.
ISSN:2001-3078
2001-3078
DOI:10.1080/20013078.2017.1321455