Critical outcomes to be included in the Core Outcome Set for nutritional intervention studies in older adults with malnutrition or at risk of malnutrition: a modified Delphi Study

• Published in: European journal of clinical nutrition 2024-08, Vol.78 (8), p.663-669
• Main Authors: Mendonça, Nuno, Avgerinou, Christina, Çavdar, Sibel, Cederholm, Tommy, Cruz-Jentoft, Alfonso J., Torbahn, Gabriel, Sieber, Cornel, Siebentritt, Hanna M., Kiesswetter, Eva, Volkert, Dorothee, Visser, Marjolein
• Format: Article
• Language: English
• Subjects: 692/699/1702/295; 692/700/1518; 692/700/2814; Adults; Appetite; Body weight; Clinical Nutrition; Clinical outcomes; Clinical trials; Diet; Dietary intake; Epidemiology; Food intake; Health care; Health policy; Internal Medicine; Long-term care; Malnutrition; Medical research; Medicine; Medicine & Public Health; Metabolic Diseases; Muscle strength; Nutrition therapy; Older people; Public Health; Quality of life; Risk; Surveys
• ISSN: 0954-3007; 1476-5640; 1476-5640
• DOI: 10.1038/s41430-024-01444-6

Introduction As part of the development of an agreed minimum set of outcomes or Core Outcome Set (COS) for future nutritional intervention trials in older adults with malnutrition or at risk of malnutrition, this work reports on the Delphi surveys and final consensus. Methods Outcomes from a scoping review were incorporated into a two-round Delphi survey. Researchers and healthcare professionals experienced in malnutrition in older adults were invited to take part in an online survey to rate 38 selected outcomes on a nine-point Likert scale ranging from ‘not important’ to ‘critical’ for their setting (community, hospital, or long-term care). Consensus for inclusion was reached when ≥75% (or ≥60% if a patient-reported outcome) of the participants scored the outcome as ‘critical’ and