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Amyloid: Toward terminology clarification Report from the Nomenclature Committee of the International Society of Amyloidosis

The modern nomenclature of amyloidosis now includes 25 human and 8 animal fibril proteins. To be included in the list, the protein has to be a major fibril protein in extracellular deposits, which have the characteristics of amyloid, including affinity for Congo red with resulting green birefringenc...

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Bibliographic Details
Published in:Amyloid 2005-03, Vol.12 (1), p.1-4
Main Authors: Westermark, Per, Benson, Merrill D, Buxbaum, Joel N, Cohen, Alan S, Frangione, Blas, Ikeda, Shu-Ichi, Masters, Colin L, Merlini, Giampaolo, Saraiva, Maria J, Sipe, Jean D
Format: Article
Language:English
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Summary:The modern nomenclature of amyloidosis now includes 25 human and 8 animal fibril proteins. To be included in the list, the protein has to be a major fibril protein in extracellular deposits, which have the characteristics of amyloid, including affinity for Congo red with resulting green birefringence. Synthetic fibrils with amyloid properties are best named 'amyloid-like'. With increasing knowledge, however, the borders between different protein aggregates tend to become less sharp.
ISSN:1350-6129
1744-2818
DOI:10.1080/13506120500032196