Chlamydia pneumoniae in children undergoing adenoidectomy

Chlamydia pneumoniae is a common respiratory pathogen which is often found in paediatric populations. Little is known about the true colonization rate and the localization of the bacteria in the respiratory tract. In this study, immunohistochemistry was used to examine adenoids from 69 children unde...

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Bibliographic Details
Published in:Acta Paediatrica 2001-02, Vol.90 (2), p.126-129
Main Authors: Normann, E, Gnarpe, J, Nääs, J, Gnarpe, H, Karlsson, MG, Wettergren, B
Format: Article
Language:English
Subjects:
Adenoid
Adenoidectomy - methods
Adenoids - immunology
Adenoids - microbiology
Adenoids - surgery
Adolescent
Antibodies, Monoclonal - immunology
Bacterial diseases
Biological and medical sciences
Child
Child, Preschool
children
Chlamydia Infections - immunology
Chlamydia Infections - microbiology
Chlamydia pneumoniae
Chlamydophila pneumoniae - immunology
Chlamydophila pneumoniae - isolation & purification
Ent and stomatologic bacterial diseases
Female
Human bacterial diseases
Humans
Immunohistochemistry
Infant
Infectious diseases
Male
Medical sciences
Polymerase Chain Reaction
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Summary:Chlamydia pneumoniae is a common respiratory pathogen which is often found in paediatric populations. Little is known about the true colonization rate and the localization of the bacteria in the respiratory tract. In this study, immunohistochemistry was used to examine adenoids from 69 children undergoing elective adenoidectomy. Throat swabs for polymerase chain reaction (PCR) and blood samples for serology were also obtained. Chlamydia pneumoniae was demonstrated in the adenoids by immunohistochemistry in 68 of the children. Five children (7%) had a positive C. pneumoniae PCR test from throat swabs and 14 children (20%) had detectable antibodies by the microimmunofluorescence technique. Conclusion: The results suggest that C pneumoniae is a common finding in the adenoids of children undergoing adenoidectomy. Whether or not C pneumoniae plays a pathogenic role in this patient population could not be determined from the data obtained in this investigation.
ISSN:0803-5253
1651-2227
DOI:10.1111/j.1651-2227.2001.tb00271.x