Endothelial cell antibody-mediated rejection and successful retransplantation in a heart transplanted patient

Antibody-mediated rejection (AMR) plays a significant role in cardiac allograft dysfunction, and recently a consensus regarding the diagnosis of AMR has been published. To our knowledge, it has not previously been reported that acute graft failure related to AMR, and antiendothelial cell antibodies...

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Bibliographic Details
Published in:European journal of cardio-thoracic surgery 2012-12, Vol.42 (6), p.1044-1046
Main Authors: Sigurdardottir, Vilborg, Kolsrud, Oscar, Hernandez, Nidia, Dellgren, Göran
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Biomarkers - metabolism
Cardiology. Vascular system
Clinical Medicine
Endothelial Cells - immunology
Graft Rejection - immunology
Heart Failure - surgery
Heart Transplantation - immunology
Humans
Immunoglobulin M - metabolism
Klinisk medicin
Male
Medical sciences
Pneumology
Reoperation
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
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Summary:Antibody-mediated rejection (AMR) plays a significant role in cardiac allograft dysfunction, and recently a consensus regarding the diagnosis of AMR has been published. To our knowledge, it has not previously been reported that acute graft failure related to AMR, and antiendothelial cell antibodies can successfully be diagnosed to allow the patient to receive the outlined treatment and undergo a subsequent retransplantation.
ISSN:1010-7940
1873-734X
1873-734X
DOI:10.1093/ejcts/ezs368