More tendon degeneration in patients with shoulder osteoarthritis

Purpose Tendon disorders are a major problem in the general population. It is known that rotator cuff tendinopathy contributes to osteoarthritis (OA) of the shoulder. The aim of the study was to analyse the presence of tendinopathy in patients with shoulder OA and an intact rotator cuff, using a mul...

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Bibliographic Details
Published in:Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA sports traumatology, arthroscopy : official journal of the ESSKA, 2019-01, Vol.27 (1), p.267-275
Main Authors: Ibrahim, Mustafa, Kartus, Jüri-Toomas, Steigen, Sonja Eriksson, Olsen, Randi, Meknas, Khaled
Format: Article
Language:English
Subjects:
Arthritis
Biocompatibility
Biopsy
Degeneration
Evaluation
Extracellular matrix
Humerus
Joint surgery
Knee
Medicine
Medicine & Public Health
Orthopedics
Ortopedi
Osteoarthritis
Patients
Rotator cuff
Shoulder
Surgical implants
Transmission electron microscopy
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Summary:Purpose Tendon disorders are a major problem in the general population. It is known that rotator cuff tendinopathy contributes to osteoarthritis (OA) of the shoulder. The aim of the study was to analyse the presence of tendinopathy in patients with shoulder OA and an intact rotator cuff, using a multimodal approach. Methods Thirteen consecutive patients median age 67 (52–84) years, with OA of the shoulder, and 13 consecutive control patients, with a fracture of the proximal humerus, median age 70 (51–84) years, underwent an open biopsy procedure from the biceps and subscapularis tendon in conjunction with shoulder arthroplasty. In addition to a macroscopic evaluation, the samples underwent histologic, morphologic and ultrastructural analyses in light and transmission electron microscopy. Results Macroscopic degeneration was found in 15 of 26 specimen in the OA group but in seven of 25 in the control group ( p  = 0.048). The histologic analysis revealed a non-significant difference for the total degeneration score (TDS) between the study groups. The morphologic evaluation of the samples revealed that the OA group had significantly more samples with non-homogeneous extracellular matrix (ECM), ( p  = 0.048). Ultrastructurally, the OA group revealed a significantly larger fibril diameter in the biceps tendon ( p  
ISSN:0942-2056
1433-7347
1433-7347
DOI:10.1007/s00167-018-5186-x